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NCT05727709
Dynamic Changes of Torquetenovirus (TTV) Load in Chinese Renal Transplant Recipients
Conditions: Kidney Transplant Rejection, Kidney Transplant Infection, Virus, Immunosuppression
Sex: All
Ages: 18 Years – 65 Years
Enrollment: 220
Sponsor: Tongji Hospital
Location: China
Summary
The goal of this observational study is to learn about dynamic changes of Torquetenovirus (TTV) load in Chinese renal transplant recipients.
The main questions it aims to answer are:Is there correlation between TTV load and rejection?Is there correlation between TTV load and infection?Can changes in the TTV load of kidney transplant recipients predict rejection or infection?Participants will:receive 13 follow-up visits within 1 year after kidney transplantationprovide 2 ml of whole blood for TTV load testing and other related testing at each follow-up
Eligibility Criteria
Inclusion Criteria:Receiving ABO compatible renal allotransplantation from the initiation of the study to December 31, 2023Receiving tacrolimus /mycophenolate mofetil(or mycophenolic acid)/prednisone as maintenance immunosuppression after renal transplantationReceiving universal prophylaxis for CMV infection and PJP infectionExclusion Criteria:Receiving combined liver-kidney, pancreas-kidney or heart-kidney transplantationRecipients with active hepatitis B or hepatitis C infectionRecipients with anticipated irregular follow-up
Source: ClinicalTrials.gov (NCT05727709). StuddyBuddy aggregates publicly available trial information.
