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NCT05727436
The Effect of Probiotics on Gingivitis
Conditions: Gingivitis; Chronic
Sex: All
Ages: 18 Years – 25 Years
Phase: PHASE4
Enrollment: 60
Sponsor: I.M. Sechenov First Moscow State Medical University
Location: Russian Federation
Summary
The aim of the study is to assess the effect of oral probiotics containing Streptococcus salivarius M18 on gingivitis and oral hygiene in young adults.
Eligibility Criteria
Inclusion Criteria:Aged between 18-25 yearsPermanent bite;Presence of more than 20 teeth;Absence of systemic and chronic diseases;The diagnosis of gingivitis stated clinically.Exclusion Criteria:Presence of mild, moderate or severe chronic periodontitis;Refusal to sign informed consent;Taking supplements and medication containing probiotics or prebiotics 1 months before the study;Taking antibiotics (within 3 months before the study);Allergy to the components of the drugs used in the study;Presence of immunodeficiency, taking immunosuppressants.Use of other hygiene products, immunostimulants and antibacterials, probiotics, prebiotics during the study;Refusal to take a given medication;Failure to attend check-ups.
Source: ClinicalTrials.gov (NCT05727436). StuddyBuddy aggregates publicly available trial information.