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Not Yet Recruiting NCT05727072

A Study of LY3848575 in Healthy Participants

Conditions: Healthy

Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: 1
Phase: PHASE1
Enrollment: 80
Sponsor: Eli Lilly and Company

Location: United States

Summary

The main purpose of this study is to evaluate the safety and tolerability of LY3848575 when administered either intravenously or subcutaneously in single ascending or multiple doses in healthy non-Japanese and first generation Japanese participants. The study will also assess how fast LY3848575 gets into the blood stream and how long it takes the body to remove it. The study is open to healthy participants. The study will last up to approximately 142 days excluding the screening period of 28 days.

Eligibility Criteria

Inclusion Criteria:Participants who are overtly healthy as determined by medical evaluationHave body weight of at least 50 kilograms (kg) for males and 40 kg for females, and body mass index of 18 to 30 kilograms per meter squared (kg/m²), inclusiveFor cohorts with Japanese participants: To qualify as a participant of the first-generation Japanese origin, the participant, the participant's biological parents, and all of the participant's biological grandparents must be of exclusive Japanese descent and born in JapanExclusion Criteria:Are currently enrolled in any other clinical study involving an investigational product (IP) or any other type of medical research judged not to be scientifically or medically compatible with this study.Have participated, within the last 3 months, in a clinical study involving an IP.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05727072). StuddyBuddy aggregates publicly available trial information.