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NCT05726045
Increasing Smoking Cessation Success Through Sleep-amplified Memory Consolidation
Conditions: Tobacco Use Disorder
Sex: All
Ages: 18 Years – 65 Years
Phase: NA
Enrollment: 140
Sponsor: Central Institute of Mental Health, Mannheim
Location: Germany
Summary
The goal of this subproject is to examine the hypothesized improvement of treatment with chess-based training and sleep enhancement, both together and on their own, in smokers.Participants will undergo fMRI measurements, sleep monitoring.
They will then be assigned to one of the four experimental groups, including high-intensity interval training with or without chess-based training.
Eligibility Criteria
Inclusion Criteria:severe tobacco use disorder (TUD) according to DSM-5sufficient ability to communicate with investigators and answer questions in both written and verbal formatability to provide fully informed consent and to use self-rating scalesright-handednessHIIT can be performed without the risk of side effect (medical sports check)Exclusion Criteria:severe internal, neurological, and/or psychiatric comorbidities; other Axis I mental disorders other than TUD according to ICD-10 and DSM 5 (except for mild depression, i.e.
F32.0, adjustment disorder and specific phobias) in the last 12 monthshistory of brain injurysevere physical diseasescommon exclusion criteria for MRI (e.g.
metal, claustrophobia)positive drug screening (opioids, benzodiazepines, barbiturates, cocaine, amphetamines)psychotropic medication within the last 14 dayspregnancy
Source: ClinicalTrials.gov (NCT05726045). StuddyBuddy aggregates publicly available trial information.