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NCT05724550
Diaphragm Function After Reversal of Rocuronium-induced Neuromuscular Blockade With Sugammadex or Neostigmine in Children
Conditions: Neuromuscular Block, Residual
Sex: All
Ages: 2 Years – 7 Years
Healthy volunteers: 1
Phase: NA
Enrollment: 82
Sponsor: Seoul National University Hospital
Location: Korea, Republic of
Summary
This study is to evaluate the recovery of diaphragm function and atelectasis after reversal of neuromuscular blockade with Neostigmine and Sugammadex using lung ultrasound and diaphragm ultrasound for children aged 2 to 7 who are scheduled for the surgical procedure under general anesthesia.
Eligibility Criteria
Inclusion Criteria:Patients between the ages of 2 and 7 who are scheduled for surgery lasting more than 1 hour under general anesthesia using a neuromuscular blocking agentExclusion Criteria:Patients with a history of severe respiratory disease with a high risk of bronchoconstrictionPatients with abnormal findings on preoperative chest radiography such as severe atelectasis, pneumothorax, pleural effusion, or pneumonia.Patients with severe renal or liver disease, or neuromuscular diseasePatients with a history of allergy to drugs (sugammadex, rocuronium neostigmine)Patients with significant bradycardiaPatients scheduled for surgery where estimated blood loss during surgery is expected to be more than 30% of estimated blood volume, or cases where fluid imbalance is expected to be severe during surgerypatients scheduled for lung parenchyme/diaphragm/thoracic surgeryother researchers considered it inappropriate to participate in research.
Source: ClinicalTrials.gov (NCT05724550). StuddyBuddy aggregates publicly available trial information.