MalnutritiOn Assessment With biOelectrical impedaNce Analysis in gastRic Cancer patIentS Undergoing Multimodal trEatment

The aim of this single-arm prospective, multicenter, cross-sectional study is to evaluate the nutritional status and body composition on tumor regression grade with bioelectrical impedance analysis in gastric cancer patients undergoing multimodal treatment. Results of this study will reveal whether nutritional status and body composition assessment based on bioelectrical impedance analysis will become a validated and objective tool to support clinical decisions in gastric cancer patients undergoing multimodal treatment.

Inclusion Criteria:Age ≥ 18 yearsHistologically confirmed gastric adenocarcinoma (or undifferentiated carcinoma)Stage II - III disease (cT2 cN+ and cT3-T4 cN+/-) based on the 8th edition of TNM classificationQualification for multimodal treatment by the decision of the multidisciplinary tumor boardExclusion Criteria:Early gastric cancer (cT1N0-3M0) scheduled for endoscopic treatment by multidisciplinary teamGastric stump carcinomaDistant metastasisUpfront surgeryOther malignanciesContraindications to bioelectrical impedance analysis (e.g., implanted cardiac devices, metal implants or pregnancy)