Modulation of Sensory Acuity With Transcranial Magnetic Stimulation (TMS)

The purpose of this research study is to understand how the brain processes and controls speech in healthy people. The investigators are doing this research because it will help identify the mechanisms that allow people to perceive their own speech errors and to learn new speech sounds, which may be applied to people who have communication disorders. 15 participants will be enrolled into this part of the study and can expect to be on study for 4 visits of 2-4 hours each.

Inclusion Criteria (Control):English-speaking adultsnormal hearing and speechno history of stroke or neurological conditionsExclusion Criteria:Native language other than EnglishAny neurological disorders other than the disorder of interestAny history of hearing disordersUncorrected vision problems that prevent participants from seeing visually-presented stimuliSignificant cognitive impairments that prevent participants from carrying out the task or from giving informed consentVulnerable populations (minors and prisoners)Additional exclusionary criteria for TMS:Implanted paramagnetic materials (metal clips, plates, pacemakers, etc.)Increased risk in the event of a seizureSerious heart diseaseIncreased intracranial pressurePregnancyHistory of seizuresFamily history of epilepsyEpileptogenic medicationsChronic or transient disruption of sleep (including jet lag)History of faintingChronic or transient increase in stressful experiencesUse of illegal drugs