Difference Between Interval and Continous Intradialytic Exercise on Functional Capacity in Hemodialysis Patient

The goal of this study is to find out the effect of interval versus continous intradialytic training on muscle quality index and functional capacity in Hemodialysis patients. The main question it aims to answer is:Does interval versus continous intradialytic training have an effect on muscle quality index and functional capacity in hemodialysis patients? Patients will be assigned randomly by computerized block randomization into two groups:Group (A): 30 patients will participate in 8 weeks of aerobic exercise in the form of high intensity interval training (HIIT) intradialytic pedaling exercise plus hemodialysis (3 sessions per week).Group (B): 30 patients will participate in 8 weeks of aerobic exercise in the form of moderate intensity continous training (MICT) intradialytic pedaling exercise plus hemodialysis (3 sessions per week) . primary and secondary variables will be measured before starting treatment and after completion (after 2 months )

Inclusion Criteria:Age between 45- 55 years.Male sex included.Patients with grade 5 chronic renal failure on hemodialysis.Patients are on hemodialysis for 1-3 years.Body mass index (BMI) range from 25-34.9 Kg/m2.They will be medically and psychologically stable.Receiving their physician-prescribed pharmacotherapy regularly.Agree to participate by signing an informed consent form.Exclusion Criteria:Inability to comprehend and follow instructions as in dementia or speech problems such as dysphasia.Patients with unstable angina, uncontrolled cardiac arrhythmia, decompensated heart failure, persistent systolic blood pressure (BP) greater than 200 mmHg, persistent diastolic BP greater than 120 mmHg, acute pericarditis or myocarditis.Acute systemic infection.Presence of malignant disease.Patients with Diabetes Mellitus.Patients with Lupus Nephritis.Patients with chronic obstructive lung disease, restrictive lung disease or chronic chest infection.Severe obesity (BMI > 35).Chronic inflammatory orthopedic disorders and rheumatoid arthritis.Patients with muscle injuries or neuromuscular disorders (muscular dystrophy, myasthenia gravis, myopathy, multiple sclerosis and peripheral neuropathy).