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Recruiting NCT05722314

ENDOMED: Evaluation of the Evolution of Endometriosis Lesions on Imaging Under Medical Treatment

Conditions: Endometriosis Pelvic

Sex: Female
Ages: 18 Years – 49 Years
Enrollment: 100
Sponsor: University Hospital, Clermont-Ferrand

Location: France

Summary

Endometriosis is a difficult disease to diagnose because the symptoms are varied, unspecific and inconsistent from one patient to another. Magnetic resonance imaging is the gold standard for the diagnosis, staging and follow-up of this pathology. Moreover, the management of endometriosis can be medical or surgical depending on the severity and location of the lesions and the patient's expectations. The recommendations of the National College of Obstetricians and Gynecologists and the French National Health Authority are medical treatment first in a certain number of situations. These patients undergoing medical treatment then require close clinical and radiological follow-up in order to evaluate the effectiveness of the treatment and the evolution of the disease. The literature describes the appearance of endometriosis lesions on pelvic MRI quite well for the establishment of the diagnosis, but there are few data on the evolution and imaging description of these lesions when hormonal treatment is in progress. Thus, we decided to evaluate and describe the evolution of endometriosis lesions on magnetic resonance imaging under medical treatment and to examine a correlation between this radiological evolution and the clinical evolution of the patients.

Eligibility Criteria

Inclusion Criteria:No history of endometriosis surgeryDiagnosis of endometriosis suspected by an MRI performed or reviewed in a reference centerPresence of symptomatology requiring medical treatmentExclusion Criteria:Pregnant or postmenopausal patientNot speaking French, not affiliated to the french social security systemMinors or under guardianshipNeed for surgical management in the first instanceContraindication to MRI (claustrophobia, renal insufficiency, gadolinium allergy, intracorporeal presence of metallic implant)

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Source: ClinicalTrials.gov (NCT05722314). StuddyBuddy aggregates publicly available trial information.