Impact of Periodontal Treatment on Growth Differentiation Factor-15 Levels

Sex: All

Ages: 30 Years – 65 Years

Healthy volunteers: 1

Phase: NA

Enrollment: 46

Sponsor: University of Catania

Summary

In light of the controversy that are already approved but that however still exists regarding the efficacy and influence the management of Periodontitis, the aim of this study was to evaluates, at 6-months follow-up, the post-treatment clinical and serum parameters in patients with periodontitis, treated by either Full Mouth Scaling and Root Planing (FM-SRP) treatment versus conventional oral hygiene treatment on serum CRP and Growth differentiation factor-15 levels.

Eligibility Criteria

Inclusion Criteria:good condition of general healtha minimum of 2 teeth for each quadrant withPocket Depth (PD) ranging from 4-6 mmno involvement of the furcationa minimum of a six teeth per quadrant, respectivelyExclusion Criteria:periodontal therapy during the last 12 monthsassumption of antibiotics during the last 6 monthspregnancyany systemic condition which might affect the effects of the study treatmentprevious or current radiation or immunosuppressive therapiesuse of mouthwash containing antimicrobials during the previous 3 monthsno use of hormonal contraceptivesmedication by anti-inflammatory and immunosuppressive drugsprevious history of hard drinkingsmokingclass II and III tooth mobility

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05720481). StuddyBuddy aggregates publicly available trial information.