Primary Eosinophilic Colitis in Symptomatic Patients.

The aim of the present study was to know the prevalence of primary eosinophilic colitis(PEC) in patients with lower gastrointestinal symptoms including diarrhea and chronic abdominal pain for which no other causes were identified.

Inclusion Criteria:All in- patients and out- patients above 18 y old undergo colonoscopy unit in Al Raghy hospital with unexplained lower symptoms including abdominal pain ,diarrhea, IBS predominant diarrhea, between , between February 2023 and December 2024 andExclusion Criteria:Cases diagnosed with 2ry causes for colonic eosinophilia.Patients with a known or compensated organic disease associated with diarrhea and alarm features (e.g., involuntary weight loss > 10% of the baseline weight, within the past 6 months.Patients with anemia, cancer and history of organ transplantation.Patients with HIV-AIDS infection.Patients under regular treatment with clozapine, carba-mazepine, rifampin, tacrolimus, gold salts, or non steroidal anti-inflammatory drugs, for 6 months prior to disease onset.Patients contraindicated for colonoscopy or biopsy, and patients with incomplete colonoscopy or inadequate bowel cleanliness at the time of the study .