Portable Oxygen Concentrator in Non-hospitalized Patients With Chronic Heart Failure

This is a one-day, proof-of-concept, pilot study of portable oxygen concentrator (POC) administration and Six Minute Walk Test (6MWT) distance in patients with stable chronic heart failure.

Inclusion Criteria:Adult male or femaleDiagnosed with chronic stable heart failureNYHA functional class II to ambulatory class IVPeripheral oxygen saturation on fingertip pulse oximetry (SpO2) ≤96% at restWillingness and ability to use a POC and with no allergy to cannula materialPatient with the capacity to provide informed consentExclusion Criteria:Contraindication to the use of POCPatient currently hospitalized or requiring hospitalizationCurrent acute decompensated HF requiring augmented therapy with vasodilator agents, and/or inotropic drugs, and/or augmented therapy or i.v. therapy with diureticsHistory of acute coronary syndrome (unstable angina or myocardial infarction) within 3 months prior to study enrollmentPatient unable to walkPatient who should be excluded in the opinion of the investigatorParticipation in another interventional clinical trial within 30 days of signing the Information and Consent Form (ICF)Pregnant female patient