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NCT05718934
Low Dose of Sugammadex vs Neostigmine and Glycopyrrolate for the Reversal of Rocuronium
Conditions: Neuromuscular Blockade
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: 1
Phase: PHASE4
Enrollment: 144
Sponsor: Ciusss de L'Est de l'Île de Montréal
Location: Canada
Summary
The aim of this study is to compare the use of a low dose sugammadex and neostigmine combined to glycopyrrolate to reverse a rocuronium induced moderate neuromuscular blockade.
Eligibility Criteria
Inclusion Criteria:ASA 1-3 patients,Undergoing general anesthesia with rocuronium induced NMB,TOF 1-3 at the end of surgery,BMI < 36 kg.m-2,Age > 18 years oldExclusion Criteria:History of coronary artery disease and unstable before surgeryHistory of serious cardiac arrhythmia (including atrial fibrillation)Renal or hepatic dysfunctionObstructive sleep apnea requiring continuous positive airway pressure (CPAP) machineNeuromuscular diseaseAllergy to any drug used in the study protocol
Source: ClinicalTrials.gov (NCT05718934). StuddyBuddy aggregates publicly available trial information.
