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Completed
NCT05718596
Quantitative Assessment of the Efficacy of Sweeps Laser Activation Systems
Conditions: Periapical Periodontitis, Polymerase Chain Reaction, Enterococcus Faecalis Infection
Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: 1
Phase: NA
Enrollment: 20
Sponsor: Istanbul Medipol University Hospital
Location: Turkey
Summary
Aim of the present study was to determine the intraradicular microbiota of previously root canal-treated teeth with apical periodontitis using droplet digital polymerase chain reaction (ddPCR) and to investigate the antibacterial effectiveness of different irrigation activation methods [ Sweeps laser and PUI group ] that will make classical chemomechanical preparation more effective.
This superiority, parallel, randomized clinical trial was conducted in the clinic of the Endodontic Department, Faculty of Dentistry, Istanbul Medipol University, Istanbul.
20 patients with apical periodontitis (one tooth each) were randomly allocated into two groups according to the used (n=10, for each): the Sweeps laser group (A) or the vdw ultra group (B).
Total bacterial loads, as well as the amount of Enterococcus faecalis (E.faecalis) were determined before (S1) and after (S2) chemomechanical preparation and finally, after intracanal medication (S3) by means of ddPCR.
Eligibility Criteria
Inclusion Criteria:root canal-treated teeth exhibiting clinical and radiographic evidence of chronic apical periodontitis lesions.Teeth with lesion apical periodontitisRadiographically, the diameter of the periapical radiolucency ranged from 2 to 7 mm.The teeth had intact coronal restorations, with no obvious exposure of the root-filling material to the oral cavity.Selected teeth had enough crown structure for adequate isolation with a rubber dam and showed an absence of periodontal pockets or attachment level deeper than 4 mm.Exclusion Criteria:teeth from patients who had received antibiotics within the previous 3 months or who had any general disease, teeth that could not be properly isolated with rubber dam, teeth with absence of coronary sealing, teeth with periodontal pocket depth >4 mm; and teeth with crown/root fracture.
Only one tooth was included from each patient.
Source: ClinicalTrials.gov (NCT05718596). StuddyBuddy aggregates publicly available trial information.
