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Completed
NCT05717751
Predictors of Para-aortic Lymph Node Metastasis of Cervical Cancer
Conditions: Locally Advanced Cervical Cancer
Sex: Female
Ages: 18 Years – 75 Years
Enrollment: 452
Sponsor: Chongqing University Cancer Hospital
Location: China
Summary
The goal of this observational study is to identify predictive factors and to develop a risk model predicting para-aortic lymph node metastasis in patients with locally advanced cervical cancer based on the analysis of surgical staging results.
The main questions it aims to answer are:What are the risk factors to predict para-aortic lymph node metastasis in patients with locally advanced cervical cancer?What is the indication for prophylactic extended-field radiation therapy in patients with locally advanced cervical cancer Individual data of patients with locally advanced cervical cancer treated with surgical staging at our institution from 2020 to 2022 were pooled analysed.Multivariate Logistic regression analysis was used to identify the predictive factors and to develop the prediction model.
Eligibility Criteria
Inclusion Criteria:In 2018, the International Federation of Obstetrics and Gynecology (FIGO) stage was Ib3 IIA2-IVA;It was treated initially without surgical and chemotherapy.Squamous cell carcinoma, adenocarcinoma and adeno-squamous cell carcinoma were confirmed by histopathology.Abdominal pelvic CT, MRI or PET/CT were performed before treatment.Patients with successful surgical staging and the pathological data of para-aortic lymph node were obtained.Exclusion Criteria:Patients were excluded if the histopathological type was not squamous cell carcinoma or Adenocarcinoma, and the data of LN status was not available.
Source: ClinicalTrials.gov (NCT05717751). StuddyBuddy aggregates publicly available trial information.
