← Back to all trials
Not Yet Recruiting
NCT05717647
Cerebral Oxygenation and Metabolism and Severe Head Injury in Paediatrics (COMetSHIP)
Conditions: Traumatic Brain Injury
Sex: All
Ages: 3 Years – 16 Years
Enrollment: 50
Sponsor: Cambridge University Hospitals NHS Foundation Trust
Summary
Children suffer proportionally more head injuries than any other age group and children with head injuries have the highest mortality of all children admitted with traumatic injuries.
The investigators aim to investigate the factors that contribute to poor outcomes after paediatric acute brain injury by collecting observational and outcome data.
Much of the brain damage that results in poor outcomes actually happens in the hours and days after the injury.
This is due to several factors such as brain swelling and poor oxygen delivery to the brain.
Treatment is directed to try and protect the brain against these factors.
Current management of the head injured child focuses on monitoring pressure within the head.
However, this does not detect all the factors that cause continuing brain damage.
Special monitors that follow oxygen levels and chemical changes in the brain are used safely in adult patients but have not been widely employed in children despite their potential benefit.
There is therefore the opportunity to evaluate extra monitoring of the child brain, and in doing so, help refine the management of these patients.
Eligibility Criteria
Inclusion Criteria:Patients admitted with brain injury requiring ventilation and ICP monitoringAge group: 3 years and 16 years (children under the age of three years are excluded as the triple bolt for multimodality monitoring is not currently used for this age group)Exclusion Criteria:Bleeding diathesisPatient unlikely to survive more than 24 hours
Source: ClinicalTrials.gov (NCT05717647). StuddyBuddy aggregates publicly available trial information.