Prehabilitation to Revolutionize Oncology: Telehealth Exercise for Cognitive Triumphs (The PROTECT Trial)

The investigators propose to deliver a pilot randomized controlled trial to 40 women newly diagnosed with breast cancer and scheduled to undergo chemotherapy. The current objectives are: 1) to evaluate the preliminary efficacy of the prehabilitation physical activity (PA) intervention delivered by a physical therapist and 2) assess the intervention's feasibility, acceptability, and appropriateness. The long-term goal is to scale this intervention for implementation into the standard of cancer care to prevent, mitigate, and treat cancer-related cognitive decline (CRCD).

Eligibility Criteria:Diagnosis of breast cancer (stage I-III).Female.At least 18 years old.Scheduled to receive curative-intent chemotherapy.English speaking.Deemed fit to participate in a PA intervention by their oncologist.Not currently participating in another physical activity research study.Low active, defined by self-report as fewer than no more than 2 times per week of regular physical activity in the last six monthsAble to understand and willing to sign an IRB-approved written informed consent document.