Nociception Level Index as a Verbal Tool of Pain in Children

60 children under 6 years old, scheduled for orthopedic surgery for limb fracture or neuromuscular and bone deformities will be randomized by closed envelope method into two groups (n=30) either receiving standard pain management protocol or intraoperative NOL guided analgesia. Our study aims to evaluate the nociception monitor's effectiveness in providing adequate postoperative analgesia in pediatric patients. Besides, the difference between the amount of analgesic medication will be recorded.Data to be recorded are total intraoperative morphine and postoperative rescue analgesic consumption, NOL values, and FLACC scores.

Inclusion Criteria:American Society of Anaesthesiologists (ASA) Physical Status classification I to IIPatients whose parents will give informed consent for the studyExclusion Criteria:Refusal to take part in the studyHistory of allergies to drugs used in the study protocolHistory of premature birthDiagnosed metabolic syndromeKnown hepatic insufficiency or decreased functionKnown renal insufficiency or decreased functionDiagnosed with mental retardation