Assessment of Recovery After Adductor Canal Block Analgesia in Unilateral Prosthetic Knee Surgery

The purpose of the study is post-operative recovery from prosthetic knee surgery will be assessed by the proportion of patients entering the Accelerated Rehabilitation After Surgery program eligible for discharge from hospital at 2 days according to the following definition: Chung score ≥ 9 with no intravenous (IV) infusion, solid food, transit restored, no signs of infection and Cumulated Ambulation Score D1 ≥ 5 (if discharged on Day 1), Cumulated Ambulation Score Day 2 ≥ 10 (if discharged on Day 2), or Cumulated Ambulation Score Day 3 ≥ 11/18.

Inclusion Criteria:Patient with a score "American Society of Anesthesiologists" I to III;Patient undergoing initial unilateral prosthetic knee replacement surgery for osteoarthritis;Patient eligible for analgesia by block of the adductor canal associated with additional infiltration;Patient accepting to follow the enhanced recovery program after surgery;Patient who signed an informed consent form to participate in the study.Exclusion Criteria:Patient with a known allergy to a study product;Patient having undergone previous surgery with a prosthesis on the knee to be operated on;Patient with morbid obesity (Body Mass Index > 40);Patient with a pre-existing inability to walk;Patient with a history of chronic neuropathic pain in the leg undergoing surgery;Patient with heart failure with impaired ejection fraction;Patient with a history of drug addiction;Patient chronically taking level III analgesics;Patient taking gabapentin or pregabalin chronically;Patient with severe renal or hepatic impairment;Patient with a high level of dependence, defined by level 1 or 2 of the Iso-Ressources Group;Protected patient (under legal protection, or deprived of liberty by judicial or administrative decision);Patient unable to understand the information related to the study (linguistic, psychological, cognitive reasons, etc.);Pregnant or likely to be pregnant (of childbearing age without effective contraception) or breastfeeding;Patient participating in another clinical trial, or in a period of exclusion from another clinical trial;Patient not benefiting from a social security scheme.