Intervention for Fatigue in HCT Recipients

The purpose of this study is to assess whether a cognitive-behavioral therapy (CBT) for fatigue intervention is acceptable, feasible, and effective at managing fatigue and improving quality of life for patients following hematopoietic stem cell transplant (HCT).

Inclusion Criteria * adult patients (≥ 18 years) * have the ability to speak and read English * have undergone autologous or allogeneic transplant \> 6 months prior to enrollment * no evidence of disease relapse requiring therapy * no new other malignancy requiring therapy after transplant * report moderate to severe fatigue in the past week (FSI average severity item rating ≥ 4 of 0-10) * are currently receiving their care at the MGH Blood and Marrow Transplant Clinic Exclusion Criteria * Patients with active cognitive impairment or uncontrolled psychiatric illness such as schizophrenia that the treating clinician believes prohibits informed consent or participation in the intervention * Patients already receiving CBT care * Patients living with untreated sleep apnea * Patients with hypoxemia requiring oxygen supplementation