TMS-evoked Potentials During Repetitive Transcranial Magnetic Stimulation on the Primary Motor Cortex

This study investigates the modification of the local-to-global connectivity pattern in response to a session of repetitive transcranial magnetic stimulation (rTMS) applied to the primary motor cortex. Transcranial magnetic stimulation (TMS) will be applied to elicit electroencephalography (EEG) responses in healthy volunteers. The TMS-evoked potentials (TEPs) will be recorded and serve as a reflection of cortical reactivity to TMS.

Inclusion Criteria:Healthy men and womenSpeak and understand EnglishExclusion Criteria:Drug addiction defined as the use of cannabis, opioids or other drugsPrevious neurologic, musculoskeletal or mental illnessesLack of ability to cooperateHistory of chronic pain or current acute painContraindications to rTMS application (history of epilepsy, metal in the head or jaw etc.).Failure to pass the "TASS questionnaire" (TASS = Transcranial Magnetic Stimulation Adult Safety Screen)