Laparoscopic Versus Open Right Colectomy for Right Colon Cancer

The purpose of this research protocol is to compare open versus laparoscopic right colectomy (according to the CME technique of complete mesocolic excision) for right colon cancer. This study will be designed as a prospective randomized controlled trial. The comparison of the two techniques will include endpoints regarding the quality characteristics of the specimens and the oncological results. In addition, the effectiveness of the two methods will be evaluated in terms of the early and late postoperative period.

Inclusion Criteria:Histologically confirmed right colon cancer (cecum, ascending colon, hepatic flexure)Surgical resection based on the CME principlesPatient 18 to 90 years oldAmerican Society of Anesthesiologists score ≤IIIΤ≤3Elective operationSigned informed consent of the patientExclusion Criteria:Non elective operation (hemorrhage, perforation, obstruction)Locally advanced disease (T4)Distant metastases (Stage IV)American Society of Anesthesiologists ≥IVPrevious laparotomyBMI >35 kg/m2Active sepsis or systemic infectionUntreated physical and mental disabilityPregnancy or breast-feedingLack of compliance with the protocol processNon-granting of signed informed consent