Cholecystitis From a Microbiological and Histopathological Perspective

Conditions: Calculous Cholecystitis, Antibiotic Resistant Infection, Gallbladder Inflammation

Sex: All

Ages: 18 Years – N/A

Healthy volunteers: 1

Enrollment: 60

Sponsor: Organkirurgisk afdeling, sygehus lillebælt, Kolding

Summary

The aim of this project is to investigate the presence of bacteria in the gallbladder wall and the bile in patients undergoing cholecystectomy, to determine if the standard empirical antibiotic treatment used currently is effective against the most common pathogens.

Eligibility Criteria

Inclusion Criteria:Age above 18 yearsSigned consent formPatients having cholecystectomy performed at the Department of Surgery, Sygehus Lillebælt, Kolding.Exclusion Criteria:Administration of any type of antibiotics one month prior to surgery in the control group.Previous instrumentation of the bileductsPrevious clinical acute cholecystitis treated conservatively with antibioticsPatients will be precluded from the studypopulation in cases of pPerioperative perforation of the gallbladder, or conversion to open cholecystectomy or in cases of failed attempts to extract bile or samples from the gallbladder wall.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05712733). StuddyBuddy aggregates publicly available trial information.