← Back to all trials
Not Yet Recruiting
NCT05709873
Narcolepsy Nightmare Study
Conditions: Narcolepsy, Narcolepsy Type 1, Narcolepsy With Cataplexy, Narcolepsy Type 2, Narcolepsy Without Cataplexy
Sex: All
Ages: 18 Years – N/A
Phase: NA
Enrollment: 10
Sponsor: Northwestern University
Location: United States
Summary
The goal of this clinical trial is to test two behavioral treatments for nightmares in adults with narcolepsy.
The main questions it aims to answer are:Is imagery rehearsal therapy (IRT) effective for narcolepsy-related nightmares?Does adding targeted dream control (TDC) to IRT make it more effective?Participants will be randomized to one of two treatment groups and will be asked to:Complete a daily log of sleep symptoms for up to 13 weeks.Attend 5-7 sessions of treatment.Complete questionnaires before and after treatment.Go to the research lab in Evanston, IL to complete a sleep study during a daytime nap.
Eligibility Criteria
Inclusion Criteria:Diagnosis of narcolepsyAge 18 or olderSpeak EnglishLive in the United States and able to attend study appointments in Evanston, ILReceiving standard medical care for narcolepsySleep and psychiatric medications stable for at least 3 monthsNightmare frequency of ≥3 times per weekNightmare Disorder Index score indicates probable nightmare disorderAble and willing to not take wake-promoting medications on day of lab visitExclusion Criteria:History of a neurological disorder that might alter EEGCurrently engaged in psychotherapyPrevious behavioral treatment for nightmaresMedical, psychiatric, or cognitive condition which would interfere with ability to engage in the treatmentUntreated sleep apnea (AHI ≥ 5)
Source: ClinicalTrials.gov (NCT05709873). StuddyBuddy aggregates publicly available trial information.