Phase II Cohort of Spinal Stereotactic Radiotherapy in Patients Using a MR LINAC

To learn whether giving spinal stereotactic radiosurgery (SRSS) that uses a more advanced imaging scan method called Magnetic Resonance imaging with a Linear Accelerator (MR-LINAC) during treatment will lead to improved responses to treatment and better quality of life. SRSS is radiation therapy given to the area around your spine.

INCLUSION CRITERIA:Age ≥ 18 years oldRadiographically documented disease of the spine within 4 weeks of registration (candidates with or without epidural disease allowed)Candidate for spine SRS/SBRT as determined by treating Radiation Oncologist or Multidisciplinary Spine Conference reviewMaximum of 3 contiguous vertebral levels involved with metastasis in the spine to be irradiated allowedDiagnosis of cancer documentedMotor strength ≥ 4 out of 5 in the extremity affected by the level of spinal disease planned for radiationKarnofsky Performance score (KPS) ≥ 40 or ECOG score ≤ 3EXCLUSION CRITERIA:Patients with highly radiosensitive histologies likely to respond to conventional radiation therapy alone (ie lymphoma, multiple myeloma, etc)Patients who are unable to undergo MRI of the spine with contrastPatients who are pregnant