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Recruiting NCT05708885

Striated Esophageal Motor Function Modulation in Health and Disease

Conditions: Dysphagia, Esophageal

Sex: All
Ages: 18 Years – 90 Years
Healthy volunteers: 1
Phase: NA
Enrollment: 557
Sponsor: Medical College of Wisconsin

Location: United States

Summary

The investigators hypothesize that striated esophagus deglutitive motor function is modulated by pharyngeal phase swallowing biomechanics.

Eligibility Criteria

Inclusion Criteria:Healthy subjects aged 18 to 90 years.Patents with dysphagia but normal high resolution esophageal manometric findings defined by the Chicago classification.Exclusion Criteria:Anyone less than 18 years old.Patients with recent head and neck cancer (<1 month post-surgery or <3 months post-chemo radiation.Patients suffering from muscle diseases like muscular dystrophies, myopathies.Patients with neuro-muscular junction disorders myasthenia gravis, Eaton-Lambert disorders.Patients having history of allergy to lidocaine or barium.Patients who are pregnant or lactating.Patients who are medically unstable.Patients who are unable to apply the exerciser independently or with the help of a caregiver.Patients who lack cognition.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05708885). StuddyBuddy aggregates publicly available trial information.