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Recruiting
NCT05708885
Striated Esophageal Motor Function Modulation in Health and Disease
Conditions: Dysphagia, Esophageal
Sex: All
Ages: 18 Years – 90 Years
Healthy volunteers: 1
Phase: NA
Enrollment: 557
Sponsor: Medical College of Wisconsin
Location: United States
Summary
The investigators hypothesize that striated esophagus deglutitive motor function is modulated by pharyngeal phase swallowing biomechanics.
Eligibility Criteria
Inclusion Criteria:Healthy subjects aged 18 to 90 years.Patents with dysphagia but normal high resolution esophageal manometric findings defined by the Chicago classification.Exclusion Criteria:Anyone less than 18 years old.Patients with recent head and neck cancer (<1 month post-surgery or <3 months post-chemo radiation.Patients suffering from muscle diseases like muscular dystrophies, myopathies.Patients with neuro-muscular junction disorders myasthenia gravis, Eaton-Lambert disorders.Patients having history of allergy to lidocaine or barium.Patients who are pregnant or lactating.Patients who are medically unstable.Patients who are unable to apply the exerciser independently or with the help of a caregiver.Patients who lack cognition.
Source: ClinicalTrials.gov (NCT05708885). StuddyBuddy aggregates publicly available trial information.