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NCT05708794
Adjust-Unlikely PE
Conditions: Pulmonary Embolism (Diagnosis)
Sex: All
Ages: 18 Years – N/A
Enrollment: 200
Sponsor: Dr. Kerstin de Wit
Summary
The aim of this pilot study is to assess the feasibility of a larger study to determine the Adjust-Unlikely algorithm safety and efficiency for diagnosing PE.The pilot study objectives are to:Determine study recruitment rate, per site, per monthDetermine study 90-day loss to follow up rateEstimate of the proportion of enrolled patients who test negative for PE at initial assessment using the Adjust-Unlikely ruleEstimate of the Adjust-Unlikely algorithm efficiencyCompare excluded and missed-eligible patients to study participants: age, sex and prevalence of PE diagnoses at initial testing.The pilot study hypothesis is that the investigators can recruit at least 20 patients per month and successfully follow at least 90% of patients for 90 days.
Eligibility Criteria
Inclusion Criteria:Emergency physician decides to test for PEExclusion Criteria:Tested for PE without using the Adjust-Unlikely algorithmD-dimer level is known before Adjust-Unlikely assessmentA new indication for anticoagulation on emergency department assessment (other than pulmonary embolism) in a patient not previously prescribed an anticoagulantDeclines participationIs inaccessible for follow-upHas previously participated in this study
Source: ClinicalTrials.gov (NCT05708794). StuddyBuddy aggregates publicly available trial information.