CMV Immunity Monitoring in Lung Transplant Recipients

The purpose of this study is to determine the safety and feasibility of using a laboratory test to guide duration of antiviral prophylaxis with valganciclovir (medication used to prevent viral infections) after lung transplant. The laboratory test, inSIGHT™ CMV T Cell Immunity Panel, measures patients' immune response to a common viral infection known as cytomegalovirus (CMV). The goal of this study will be to safely decrease how long patients need to take valganciclovir based on the results of the CMV T Cell Immunity Panel.

Inclusion Criteria:Received a lung transplant, or multi-organ transplant involving a lung at NYU Langone HealthPre-existing serological immunity to CMV (R+)Able and willing to provide informed consentExclusion Criteria:Anti-thymocyte globulin induction immunosuppressionPerioperative desensitizationPregnant or breastfeeding women