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NCT05707663
Longitudinal Assessment of Brain Structure and Function in Juvenile-onset Huntington's Disease
Conditions: Juvenile Huntington Disease, Juvenile-Onset Huntington Disease
Sex: All
Ages: 6 Years – 30 Years
Enrollment: 40
Sponsor: University of Iowa
Location: United States
Summary
The goal of this observational study is to learn about brain development in Juvenile-onset Huntington's Disease (JoHD).
The main questions it aims to answer are:Is brain development different in JoHD than Adult-onset Huntington's Disease (AoHD)?Can reliable biomarkers for JoHD be found in brain structure and function?Participants will be asked to complete cognitive tests, behavioral assessments, physical and neurologic evaluation, and MRI.
Data collected will be compared to populations who are at-risk for HD and who have been diagnosed with HD as adults.
Eligibility Criteria
Inclusion Criteria:Clinical diagnosis of JoHDAged 6-30Exclusion Criteria:Metal in bodyHistory of head trauma, brain tumor, seizures or epilepsy unrelated to JoHDHistory of major surgery or serious chronic medical conditions other than JoHD
Source: ClinicalTrials.gov (NCT05707663). StuddyBuddy aggregates publicly available trial information.
