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NCT05707156
Prospective Observational Study on the Incidence of Opportunistic Fungal Infections
Conditions: Pneumocystis Jirovecii Infection, Pneumocystis, Cryptococcosis, Candidiasis, Aspergillosis
Sex: All
Ages: 18 Years – N/A
Enrollment: 2000
Sponsor: University of Colorado, Denver
Summary
Corticosteroids exposure is a common risk factor for invasive fungal infections.
Systemic corticosteroid therapy treats several medical conditions, including rejection in solid organ transplant recipients, malignancy, and autoimmune or inflammatory diseases.
Corticosteroid exposure is a well-known risk factor for developing PJP.
Still, it remains unclear how prior corticosteroid exposure influences the presentation, severity, and mortality of opportunistic fungal infections.
The investigators aim to prospectively characterize the corticosteroid use as a dose response to inform risk of invasive fungal infections.
Eligibility Criteria
Inclusion Criteria:Patients on systemic corticosteroids for more than 2 weeksExclusion Criteria:HIV infectionTransplant statusYounger than 18 years of agePrevious history of Cryptococcosis, Aspergillosis, Pneumocystis jirovecii pneumonia or invasive candidiasis
Source: ClinicalTrials.gov (NCT05707156). StuddyBuddy aggregates publicly available trial information.
