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Not Yet Recruiting NCT05705661

INFLUENCE OF HIGH FREQUENCY CHEST WALL OSCILLATION IN HOSPITALIZED PATIENTS WITH COVID-19

Conditions: COVID-19

Sex: All
Ages: 55 Years – 65 Years
Healthy volunteers: 1
Phase: NA
Enrollment: 70
Sponsor: Cairo University

Summary

INFLUENCE OF HIGH FREQUENCY CHEST WALL OSCILLATION IN HOSPITALIZED PATIENTS WITH COVID-19The purpose of this Interventional study is to investigate the effect of high frequency chest wall oscillation in hospitalized COVID-19 patients on:Inflammatory markers: Netrophil to lymphocyte ratio and CRPHemodynamic parameters (Arterial Blood Gases, Heart Rate variability, Respiratory Rate, O2 Saturation).Dyspnea, time needed for oxygen weaning, Mortality Rate and Hospital stay period.Hypotheses :This Interventional study will test the following Null hypothesis:HFCWO will not have an effect in hospitalized COVID-19 patients regarding Arterial Blood Gases, CRP, Dyspnea, Heart Rate variability, Respiratory Rate, O2 Saturation, time needed for Oxygen Weaning, Mortality Rate and Hospital Stay Period.Research Question:Is there a significant effect of high frequency chest wall oscillation (HFCWO) in Hospitalized COVID-19 Patients?

Eligibility Criteria

Inclusion Criteria:Sixty hospitalized covid-19 patients from both genders their ages will be ranged from 55 - 65 years old.Desaturated covid-19 patients with lung fibrosis are diagnosed by the physician and confirmed by chest CTDuration of illness ranged from 1 week to 2weeks.All patients have resting oxygen saturation (SpO2) from 80 - 92 %O2 therapy is delivered via Nasal cannula or face mask.All patients will approve and sign a consent form before starting the program which will include the purpose, natures and potential risks of the study which will be explained to all patients (Appendix I).Exclusion Criteria:Hemodynamically unstable patientPatient with pneumothorax (if chest tube is present)Asthmatic patientPatient with chest deformitiesPatient with pleural effusionPatient with diaphragmatic herniaPatient with cardiac and thoracic surgeryMechanically Ventilated and intubated patients.Metabolic or cardiovascular diseases.Patients have (SpO2) less than 80 %.Patient with severe lung fibrosis.

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Source: ClinicalTrials.gov (NCT05705661). StuddyBuddy aggregates publicly available trial information.