← Back to all trials
Recruiting
NCT05705245
Effects of Recruitment Manouever on Oxygenation, Oxygen Reserve Index and Postoperative Pulmonary Complications
Conditions: Obesity, Bariatric Surgery Candidate
Sex: All
Ages: 18 Years – 65 Years
Enrollment: 80
Sponsor: Balikesir University
Location: Turkey
Summary
General anesthesia and mechanical ventilation decrease pulmonar volume; attenuate small airway closure, atelectasis, and increase the rate of hypoxia and postoperative pulmonary complications.
Lung volume in obese patients decreases inversely with the increase in body mass index.
Obesity is associated with increased atelectasis, hypoxia and postoperative pulmonary complication rates during anesthesia .
Alveolar recruitment maneuver is a technique where high positive end-expiratory pressure (PEEP) is applied for for short periods, follwed by a continuous PEEP appşication throughout surgery.
This has become a standard practice during anesthesia in recent years.
Oxygen reserve index (ORi) is an index measured with a non-invasive finger-tip sensor and shows the oxygen content of the venous blood.
It is effective at high oxygen levels and may indicate the presence of hyperoxia.
Our aim is to examine the effect of alveolar recruitment maneuver on oxygenation parameters under anesthesia and the correlation with ORi in morbidly obese patients.
Eligibility Criteria
Inclusion Criteria:Bariatric surgery general anesthesia and mechanical ventilation via orotracheal entubation Age between 18-65 ASA I-III BMI > 40 m-2Exclusion Criteria:Previous history of thorasic surgery, pneumothorax Chemo or Radiotherapy to the chest within 2 months History of Respiratory disease (COPD, emphysema, pneumonia, lung malignancy, Lung Bulla ) Emergency surgery Cardiovascular, renal, hepatic, neuromuscular disease İntracrabial pathology or trauma High intraoptic pressure Pulmonary Hypertension Pregnancy Criticall illness, or history of mechanical ventilation within 1 month
Source: ClinicalTrials.gov (NCT05705245). StuddyBuddy aggregates publicly available trial information.