RCT Comparing Avatar Intervention to Supportive Intervention to Reduce Cannabis Use in Patients With Psychotic Disorders

The goal of this clinical trial is to conduct a single-blind randomized controlled trial to verify whether the Avatar Intervention has greater efficacy over supportive intervention to reduce cannabis use in patients with psychotic disorders. The primary outcomes are reductions in cannabis use, cannabis use disorder severity, and increased quality of life.

Inclusion Criteria:Males or females over 18 years of age who meet the DSM-5 criteria for CUD (≥4 criteria) ;Patients will meet the DSM-5 criteria for schizophrenia, schizoaffective disorder, or bipolar disorder with psychotic symptoms. Diagnoses will be established with the Structured Interview for DSM-5 (SCID-5).Exclusion Criteria:Current SUD for a substance other than cannabis ;Ongoing pharmacological or psychological treatment for CUD ;Ongoing detoxification for cannabis withdrawal ;Presence of neurological disorders ;Presence of a severe and unstable physical illness ;Inability to provide consent.