Investigation of the Neurovegetative Pattern in Patients With Thoracic Aortic Aneurysms (TAA)

The goal of this observational cross-sectional study is to learn about vagal features in patients with syndromic and non-syndromic TAA. The main question it aims to answer is to highlight a functional condition that could help stratify patients with TAA on the risk of aortic complications.Participant will take part by standing in supine position for 10 minutes and during active standing for 10 minutes. In this period of time, it will be possible to acquire the signals continuously and non invasively through recorded non-invasive blood pressure and piezoelectric sensor breathing belt.

Inclusion Criteria:Patients aged 18-65 years with syndromic and nonsyndromic TAA;Signed informed consent;Patients on regular pharmacological prophylaxis (with Losartan) or naïve patients with a first diagnosisExclusion Criteria:Acute and chronic inflammatory diseases such as: liver disease, chronic renal insufficiency (creatinine > 1.5 mg/dl) and diseases affecting the thyroid system.