Long Term Followup of Patients Enrolled in MC1137, BEAUTY Study

This study gathers information and samples for further analysis as part of the BEAUTY study. The purpose of the BEAUTY study was to better understand the reasons why or why not breast cancers respond to standard chemotherapy. Collecting samples of blood and tissue and health and treatment information from patients on the BEAUTY study may help doctors identify changes that make cancer better respond to standard chemotherapy and develop better therapies for the treatment of cancer.

Inclusion Criteria:REGISTRATION - FOR PATIENTS STILL ALIVE:Enrolled in BEAUTY (MC1137 [NCT02022202]) and did not withdraw consent while enrolled on BEAUTY for either specimen collection or long-term follow-upAble to provide written informed consentWillingness to provide mandatory blood specimens for future research on breast cancer at Mayo ClinicWillingness to provide mandatory tissue specimens for future research on breast cancer at Mayo ClinicWillingness to provide consent for use of archived tumor biopsies obtained after enrollment in BEAUTY (Request tissue from prior biopsy of site of recurrence)Ability to complete questionnaires by themselves or with assistanceREGISTRATION - FOR PATIENTS WHO HAVE DIED:Enrolled in MC1137 and did not withdraw consent while enrolled on BEAUTY for either specimen collection or long-term follow-upExistence of a family member willing to provide consent for use of archived tumor biopsies obtained after enrollment in BEAUTY