Effectiveness of AV-stimulation in Immersive VR to Improve Visual Perception and Driving Performance

The goal of this clinical trial is to evaluate the effectiveness of an immersive virtual-reality (IVR) based stimulation program, in improving visual perception for people who have lost their driver's license due to perceptual or cognitive impairments.The main questions it aims to answer are:Can the 6-week IVR stimulation program help improve driving performance?Will participants experience improvement in visual detection and perception after training?Study Design Summary:Participants will be randomized into a waitlist group or intervention-first groupThe VR-based intervention will consist of training every 2 days for six weeksWaitlist group will wait 6 weeks before starting intervention at study midpoint (week 7)Intervention-first group will begin with intervention (week 1-6) and then stop intervention at study midpointParticipants will complete tests related to driving performance, visual attention, and visual fields at the start of study, midpoint, and end of studyResearchers will analyze data for changes from baseline in outcome measures.

Inclusion Criteria:Male and female > 25 years old.Visual field defects due to TBI or strokeBCVA ≥ 20/50.Previously held a valid driving license and were active drivers.Ability to follow the visual and auditory stimuli and training instructions.Online auditory test positive (-5dBHL to 60dBHL range) at 125 Hz (for research purposes only)Home Wi-Fi access.Exclusion Criteria:Both eyes with media opacity that impairs visual field testing.Inability to perform during testing and training.Cognitive/motor condition incompatible with driving simulator and/or VR.Recreational or medicinal consumption of psychoactive drugs.3 consecutive VRISE scores < 25 at inclusion.History of vertigo or dizziness.Visual neglect.Prior/current vision rehabilitation interventions.Photosensitive epilepsy.