Assessing the Effect of Abstinence Period on Semen Parameters

Sex: Male

Ages: 20 Years – 45 Years

Healthy volunteers: 1

Phase: NA

Enrollment: 100

Sponsor: Weill Medical College of Cornell University

Summary

The goal of this study is to learn about the impact of abstinence periods on sperm quality in healthy males 20-45 years of age with no significant comorbidities who are able to produce a semen sample via masturbation. The main question it aims to answer is:• Do shorter abstinence periods result in improved semen quality?Participants will provide semen samples for analysis following abstinence periods of 7 days, 5 days, 2 days, 1 day, and 3 hours.

Eligibility Criteria

Inclusion Criteria:Males, aged 20-45 yearsHealthy, no significant comorbiditiesAble to produce a semen sample by masturbationTotal sperm count ≥ 1 million spermAbnormal sperm DNA fragmentation (TUNEL assay value ≥ 20%)Exclusion Criteria:Age < 20 or > 45 yearsSignificant comorbidities, including significant cardiac, pulmonary, gastrointestinal, hematologic, or neurologic diseaseTotal sperm count < 1 million spermAspermia (semen volume = 0)Normal sperm DNA fragmentation (TUNEL assay value < 20%)

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05701163). StuddyBuddy aggregates publicly available trial information.