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Completed
NCT05700604
Hypoglycemia and Glucagon Response in CF
Conditions: Cystic Fibrosis, Hypoglycemia, Glucagon Deficiency, Pancreatic Insufficiency
Sex: All
Ages: 10 Years – 18 Years
Healthy volunteers: 1
Enrollment: 53
Sponsor: Marmara University
Location: Turkey
Summary
The goal of this clinical trial is to investigate the etiopathogenesis of isolated hypoglycemia and hypoglycemia with abnormal glucose tolerance in children with Cystic Fibrosis (CF) and to evaluate the role of glucagon and pancreatic insufficiency on hypoglycemia in CF.
The main questions it aims to answer are:Do isolated hypoglycemia and hypoglycemia with abnormal glucose tolerance have different etiopathogenesis?What is the role of pancreatic insufficiency in these two conditions?
Participants were asked to perform 3-h OGTT and to take blood samples.
Researchers compared with healthy peers to see if there is isolated hypoglycemia in OGTT and how is the glucagon response to OGTT in healthy peers.
Eligibility Criteria
Inclusion Criteria:10-18 year-old children genetically diagnosed with Cystic FibrosisRegularly followed by the department of pediatric endocrinologyExclusion Criteria:Using corticosteroid therapy in the last 3 monthsThose who had acute exacerbation in the last 3 monthsPreviously diagnosed with diabetes
Source: ClinicalTrials.gov (NCT05700604). StuddyBuddy aggregates publicly available trial information.
