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Completed NCT05693428

Influence of Anesthetics on Clinical Outcome During Cardiac Surgery in Adults

Conditions: CHD - Coronary Heart Disease

Sex: All
Ages: 45 Years – 67 Years
Healthy volunteers: 1
Phase: NA
Enrollment: 90
Sponsor: Astana Medical University

Location: Kazakhstan

Summary

Abstract Cardiac surgery in adults is associated with the occurrence of post-operative complications. Even minor complications can increase the cost of their treatment. Given the potentially preventable nature of a number of these postoperative complications, preventive methods should be used to improve outcomes after cardiac surgery. One of them, is the choice of anaesthetic technique.Objectives: To evaluate the effects of sevoflurane, isoflurane and propofol on blood oxygen transport function and body energy expenditure during cardiac surgery in adults.Materials and methods. A total of 90 patients were included in the study. All patients were divided into 3 groups: 1- (n=30) included patients who were anesthetized with propofol. The second group (n=30) consisted of patients who underwent sevoflurane inhalation anaesthesia. Group 3 (n=30) was treated with isoflurane. All patients underwent coronary artery bypass grafting under cardiopulmonary bypass.

Eligibility Criteria

Inclusion Criteria:The age is over 40 years old.coronary revascularization or >50% stenosis on coronary angiographyCHD. Multivessel coronary lesions.Participants of both sexes will be included in the studySigned informed consentExclusion Criteria:pregnancy (risk to the baby and the mother)allergenic patients (anaphylactic shock).vulnerable groups.current congestive heart failure;current unstable angina pectoris;preoperative hemodynamic instability, defined as the use of vasopressors;

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Source: ClinicalTrials.gov (NCT05693428). StuddyBuddy aggregates publicly available trial information.