Improvement of Functional Dyspepsia After Drinking Alkaline Ionized Water From Alkaline Ionizer

The goal of this clinical trial is to evaluate the effect of drinking electrolyzed alkaline reduced water (EARW) compared to drinking purified water (PW) on functional dyspepsia (FD) patients.The main question[s] it aims to answer are:Drinking EARW (EARW group) will alleviate gastrointestinal (GI) symptoms and FD symptoms compared to drinking PW (PW group).Drinking EARW will make higher the FD-related Quality of Life (FD-QOL) compared to drinking PW.Patients will drink EARW 10mL/kg/day body weight for 6 weeks according to the instruction of researcher using the experimental device installed at each patient's house. After 6 week, EARW and PW groups will be compared to evaluate effect of GI symptom and FD-related QOL.

Inclusion Criteria:Symptoms onset should start at least 6 months before diagnosis based on one or more of the following symptoms Rome IV criteria (Unpleasant postprandial fullness, early satiety, epigastric pain, epigastric burning sensation)No evidence of structural disease in gastroscopy within the last 3 monthsAged 19-70 yearsWho meets Rome IV criteria for functional dyspepsiaWho have 4 or more symptoms based on the gastrointestinal symptom rating scalePatients who voluntarily agree to participate in this study and sign a written consentExclusion Criteria:Subjects who have a history of serious malignancy including gastrointestinal malignancy, cerebrovascular disease, and heart disease within the past 6 months were excludedSubjects who have uncontrolled diabetes and hypertension despite appropriate managementSubjects who have a history of peptic ulcer or reflux esophagitis within the past 6 months were excludedSubject who have history of gastrointestinal surgery were excludedWomen who are pregnant or breastfeedingSubjects who are taking drugs that may affect the gastrointestinal tract (minimum of 2 weeks washout period is necessary before participating in the trial (Medications include H2 receptor blockers, anticholinergics, prostaglandins, proton pump inhibitors, gastromucosal protection agents, corticosteroids, non-steroidal anti-inflammatory drugs, aspirin, mucosal protective agents, etc.)Subjects who are under drugs for therapeutic purposes such as functional food that promotes gastric healthSubjects who consumed more than 14 times alcohol per week in case of man and 7 times per week in case of female in the past 1 month