Towards a Wearable Alcohol Biosensor: Examining the Accuracy of BAC Estimates From New-Generation Transdermal Technology Using Large-Scale Human Testing and Machine Learning Algorithms

The study will employ a combined laboratory-ambulatory design. Participants will engage in ambulatory assessment over the course of 14 days, wearing biosensors assessing transdermal alcohol concentration (TAC) and providing breathalyzer readings in real-world contexts. Also during this period, participants will attend three laboratory alcohol-administration sessions scheduled at one-week intervals, with alcohol dose and rate of consumption manipulated within and between participants, respectively. Laboratory visits will also double as ambulatory orientation, check-in, and close-out sessions.

Inclusion Criteria:21 years or olderdrink alcohol at least 2x weeklyExclusion Criteria:psychological or medical conditions that might contraindicate alcohol-administrationhistory of adverse reaction to type and amount of beverage used in the studycurrently seeking treatment for alcohol use disorderdoes not drink alcohol regularlytaking drugs or medications for which alcohol consumption would be contraindicatedwomen who are pregnant or are attempting to become pregnant