Expression of microRNA-133a and microRNA-208b in Acute Myocardial Infarction

Sex: All

Ages: 35 Years – 65 Years

Healthy volunteers: 1

Enrollment: 10

Sponsor: Islamia University of Bahawalpur

Summary

Cardiac-enriched micro-RNAs (miRNAs), micro RNA 208b and 133a(MiR-208b, MiR-133a)) corresponds to the health and disorders of the cardiovascular system. An intron of the cardiac myosin heavy chain gene MYH7 encodes miR-208b. It is found on chromosome 14 in humans. Identify new diagnostic biomarkers based on miRNAs, researchers examine the expression of miR-133a and 208b at various time points (04 hours, 08 hours, 12 hours, 24 hours, 48 hours) following the development of the infarct and compared it to the traditional myocardial infarction biomarkers cardiac troponine (cTnl) and Creatine kinase-MB (CK-MB).

Eligibility Criteria

Inclusion Criteria:Patients diagnosed with ST-Elevated Myocardial Infarction will be identified at the Coronary Care Unit at Ain-shams University hospitalAcute episode of Myocardial InfarctionWith No history of previous Myocardial Infarction TreatmentExclusion Criteria:Patients not diagnosed with ST-Elevated Myocardial Infarction and healthy at the Coronary Care Unit at Ain-shams 2. University hospitalPreviously Known patients of Myocardial infacrtionPrevious medication

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Source: ClinicalTrials.gov (NCT05692752). StuddyBuddy aggregates publicly available trial information.