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NCT05690542
Nanoparticles in Blood: Understanding and Controlling Protein Corona for Optimized Nanomedicine
Conditions: Coagulation Tests
Sex: All
Ages: 18 Years – 79 Years
Enrollment: 60
Sponsor: Centre Hospitalier Universitaire Dijon
Location: France
Summary
The main objective is to study the effect of engineered nanoparticles SPIONs (superparamagnetic iron oxide) on hemostasis.
Nanoparticles will be incubated in blood and platelet aggregation will be measured.
In parallel, nanoparticles will also be incubated in blood and then plasma proteins adsorbed on them will be separated and analyzed.
The proteins found on the nanoparticles will be linked to the platelet aggregation observed to help developing innovative protein functionalized nanoprobes for optimized nanomedicine.
Eligibility Criteria
Inclusion Criteria:all peopleExclusion Criteria:patient under 18 years old, legal protection measure, pregnancy
Source: ClinicalTrials.gov (NCT05690542). StuddyBuddy aggregates publicly available trial information.
