Moderate vs Deep Neuromuscular Block in Lower Pressure Pneumoperitoneum

Sex: Female

Ages: 18 Years – 65 Years

Healthy volunteers: 1

Phase: NA

Enrollment: 70

Sponsor: Universiti Sains Malaysia

Summary

The investigators hypothesized that deep neuromuscular block compare to moderate neuromuscular block would reduce the rate of increasing intraabdominal pressure and operation can be completely done in lower pressure pneumoperitoneum and would improve laparoscopic space by measuring distance from the sacral promontory to the inserted trocar in patients undergoing laparoscopic gynaecological surgery.

Eligibility Criteria

Inclusion Criteria:Age more than 18 years oldASA I or IIschedule to undergo laparoscopic gynaecological surgery (laparoscopic hysterectomy and laparoscopic ovarian cystectomy in Hospital Universiti Sains Malaysia , Kubang Kerian, KelantanExclusion Criteria:Allergy to study drugs (rocuronium, suggamadex)Serious cardiac and respiratory disease (reactive airway disease, upper respiratory tract infection)Neurological or neuromuscular disease (epilepsy, family history and history of malignant hyperthermia etc.)PregnancyMorbid obesity BMI>35

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05689957). StuddyBuddy aggregates publicly available trial information.