Vitamins D and K Effects on Vascular Function in Obese Adults.

A prospective, randomized, placebo-controlled, double-blind study that aims to evaluate the effects of combined vitamin D3 and K2-MK7 supplementation on vascular function, sympathetic tone, metabolic biomarkers and inflammatory factors in a population of overweight or obese adults and deficient or insufficient serum levels of vitamin D.

Inclusion Criteria:Vitamin D deficiency;Vitamin D insufficiency;Obesity;Overweight;Exclusion Criteria:Diabetes mellitus;Arterial coronary disease;Beta blocker use;cancer;ESRD;