Effect of the Administration of a Symbiotic (E. Faecium and Agave Inulin) on Mild Cognitive Impairment in Older Adults

Cognitive impairment is one of the fastest growing diseases in the last decades, given the significant increase in senior citizen population in Mexico and the world.Several studies have discussed the gut-microbiota-brain axis. It has been demonstrated that a balanced gut microbiota, prevents an increase in pro-inflammatory cytokines that affect specific brain areas; having an important impact at the cortical level of the hippocampus which translates to diminished cognitive function and the start of cognitive impairment symptoms.After multiple studies on the effect of the administration of symbiotics in animal models in cognition and memory, there have been positive results, observing improvement in cognition and decrement in inflammatory cytokines at hippocampus level.

Inclusion Criteria:Patients with mild cognitive impairmentPatients who sign the informed consentExclusion Criteria:Patients who do not have mild cognitive impairmentPatients with advanced cognitive impairment such as Alzheimers diseasePatients with comorbidities that influence the cognitive functions such as diabetes mellitus, cerebral ischemia or previous brain traumaPatients who do not sign the informed consent