Tranexamic Acid in Functional Endoscopic Sinus Surgery

Sex: All

Ages: 18 Years – 40 Years

Healthy volunteers: 1

Phase: PHASE4

Enrollment: 159

Sponsor: Ain Shams University

Summary

The purpose of the study is to compare the effect of oral tranexamic acid vs. intravenous in decreasing bleeding and improving the field during FESS.

Eligibility Criteria

Inclusion Criteria:American Society of Anesthesiologists grade I or II.Sex: Both sexes.Age between 18 and 40 years.Patients scheduled for FESS under general anesthesia.Exclusion Criteria:Declining to give written informed consent.History of allergy to the medications used in the study.History of venous or arterial thrombosis.history of cardiovascular diseases including AF, IHD, or hypertension.History of chest problems including pulmonary embolism, bronchial asthma and COPD.History of cerebrovascular stroke.History of drug or alcohol abuse.Taking opioids or sedative medications.Hepatic or renal failure.Bleeding disorders, antiplatelets (aspirin, clopidogrel) or anticoagulant (warfarin).

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05686005). StuddyBuddy aggregates publicly available trial information.