Invasive and Clinical Features in Patients With Brugada Syndrome Undergoing Catheter Ablation

This clinical trial aims to learn about the electrophysiological and clinical effects of radiofrequency catheter ablation in patients with Brugada syndrome. The main questions it seeks to answer are:What are the immediate effects of catheter radiofrequency ablation in cardiac electrophysiology?What is the relation between invasive and clinical features in patients with Brugada syndrome undergoing ablation? Researchers will compare ablation and control groups to see if there is a difference in clinical and invasive markers of the disease in one year of follow-up.

Inclusion Criteria:Patients with a type 1 Brugada ECG pattern, as characterized by ST-segment elevation (≥2mm) with upward concavity associated with T-wave inversion, in at least one of the right precordial leads, positioned at the second, third or fourth intercostal space, either spontaneously or induced by a provocative test with Class I anti-arrhythmic drugs according to Vaughan WilliamsPatients clinically stable for at least six months before the enrollmentAble to cope with follow-up visits up to one year after the interventionPatients who have signed the written informed consentExclusion Criteria:Pregnant womenPatients with structural heart diseasePatients with a known cardiac or systemic autonomic disorderPatients with a history of previous right ventricular outflow tract ablation