Radiation-induced Diarrhoea During Curative EBRT of Prostate and Rectal Cancer

Approx. 80% of patients with prostate and rectal cancer who receive radiation therapy (RT) experience acute radiation-induced diarrhea (RID). RID has major impact on patients' quality of life, can lead to pause or early termination of RT and chronic diarrhea. RID is poorly described with few details of type and severity of RID in clinical practice and in the literature. We are conducting an observational study in patients in patients who receive curative EBRT radiation for prostate and rectal cancer to uncover the frequency and classifications of RID.

Inclusion Criteria:Histopathologically verified prostate or rectal adenocarcinomaCommenced to start curative EBRT to the pelvis, with or without chemotherapy or with or without androgen deprivation therapy (ADT)Performance status 0-1≥ 18 years of ageUnderstanding and acceptance of written and orally informed consent in DanishExclusion Criteria:Earlier treated with EBRT or other type of radiation to the pelvisHistory of diagnosed inflammatory bowel diseaseColostomyPregnancy