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Recruiting NCT05684289

A Study Investigating the Safety, Tolerability, Drug Levels and Drug Effect of BMS-986278 in Healthy Adult Participants (Part 1) and Japanese Participants (Part 2)

Conditions: Healthy Participants

Sex: All
Ages: 35 Years – 65 Years
Healthy volunteers: 1
Phase: PHASE1
Enrollment: 60
Sponsor: Bristol-Myers Squibb

Location: United States

Summary

The purpose of this study is to evaluate the safety, tolerability, drug levels and drug effect of BMS-986278 in healthy adult participants and Japanese participants.

Eligibility Criteria

Inclusion Criteria:Participants in the Japanese cohort (Part 2) must be first generation Japanese (born in Japan, not living outside of Japan > 10 years, both parents ethnically Japanese).Body mass index (BMI) of 18.0 kilogram (kg)/meter (m)^2 through 32.0 kg/m^2, inclusive. BMI = weight (kg)/(height [m])^2.Body weight ≥ 50 kg for males and ≥ 45 kg for females.Exclusion Criteria:Any significant acute or chronic medical illness.Any gastrointestinal (GI) disease or surgery (including cholecystectomy) or other procedures (for example, bariatric procedures) that could affect drug absorption, distribution, metabolism, and excretion.Any major surgery within 4 weeks of first study intervention administration.Other protocol-defined inclusion/exclusion criteria apply.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05684289). StuddyBuddy aggregates publicly available trial information.